eGFR Clinical Calculator
Calculates Estimated Glomerular Filtration Rate using the standardized 2021 CKD-EPI creatinine equation without race coefficients.
Interactive eGFR Calculator
Mild filtration reduction. Common with physiological aging; in the absence of kidney damage markers, this may represent normal aging.
Evaluate blood pressure, HbA1c, and cardiovascular risk. Repeat test in 12 months to verify filtration trajectory.
KDIGO CKD Staging Classification & Clinical Action Guide
| Stage | eGFR (mL/min/1.73m²) | Kidney Status | Clinical Action Mandate |
|---|---|---|---|
| G1 | ≥ 90 | Normal or High | Screen for proteinuria if diabetes or hypertension present; annual observation. |
| G2 | 60 – 89 | Mild Reduction | Estimate rate of progression; review cardiovascular risk factors and medication dosing. |
| G3a | 45 – 59 | Mild to Moderate | Evaluate complications (anemia, MBD); adjust renal-cleared drug dosages. |
| G3b | 30 – 44 | Moderate to Severe | Frequent monitoring (every 3-6 months); nephrologist co-management recommended. |
| G4 | 15 – 29 | Severe Reduction | Formal nephrology care; prepare vascular access / renal replacement counseling. |
| G5 | < 15 | Kidney Failure (ESRD) | Urgent renal replacement therapy (hemodialysis, peritoneal dialysis, or transplant). |
Equation Specification: 2021 CKD-EPI Creatinine Refinement
In 2021, the National Kidney Foundation (NKF) and American Society of Nephrology (ASN) Task Force recommended the immediate adoption of the 2021 CKD-EPI creatinine equation without the race coefficient across all clinical laboratories in the United States and globally.
Related Clinical Tools
This calculator is designed for use by healthcare professionals, clinical pathologists, and patients evaluating renal reserve. It conforms to the 2021 NKF-ASN guidelines and KDIGO 2024 staging protocols.